Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553250 | 0.90 | NPC1 (0.41) | NPC1SERPINE1MAPK1HIF1AELANE | |
| SCHEMBL12954633 | 0.77 | NPC1 (0.37) | NPC1SERPINE1LMNACYP1A2CYP3A4 | |
| SCHEMBL1996387 | 0.77 | MAPK1 (0.62) | NPC1MAPK1HIF1ALMNACYP1A2 | |
| SCHEMBL1993751 | 0.76 | MAPK1 (0.47) | SERPINE1MAPK1HIF1ALMNACYP1A2 | |
| SCHEMBL12954433 | 0.76 | NPC1 (0.36) | NPC1SERPINE1LMNACYP1A2CYP3A4 | |
| SCHEMBL9142594 | 0.75 | ESR1 (0.51) | NPC1MAPK1HIF1ALMNACYP1A2 | |
| SCHEMBL27823311 | 0.75 | NPC1 (0.41) | NPC1SERPINE1LMNACYP1A2CYP3A4 | |
| SCHEMBL1998060 | 0.74 | MAPK1 (0.46) | NPC1MAPK1HIF1ALMNAMAPT | |
| SCHEMBL21292572 | 0.73 | MAPK1 (0.38) | SERPINE1MAPK1HIF1AMAPTTSHR | |
| SCHEMBL1995807 | 0.72 | MAPK1 (0.61) | NPC1MAPK1HIF1AELANELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8208836-A | — | — | None | — | — | JP | disclosed |
| JP-H08208836-A | POLYIMIDE CONTAINING FLUORINE | CHISSO CORP | 1996-08-13 | — | — | JP | disclosed |