Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591076 | 0.98 | TDP1 (0.41) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL2415896 | 0.79 | TDP1 (0.40) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL27625285 | 0.79 | TDP1 (0.43) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL29222920 | 0.78 | TSHR (0.46) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL8164447 | 0.76 | TSHR (0.42) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL19105301 | 0.76 | TSHR (0.42) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL11599637 | 0.75 | — | — | |
| SCHEMBL770455 | 0.74 | TSHR (0.41) | TDP1TSHRCYP3A4MAPTCACNA1B | |
| SCHEMBL4672425 | 0.74 | — | — | |
| SCHEMBL16026506 | 0.73 | TDP1 (0.43) | TDP1TSHRCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494718-A | GLASS FIBER REINFORCED THERMOPLASTIC MATERIAL | THE GEON COMPANY (US) | 1996-02-27 | — | — | US | disclosed |
| US-4118352-A | CONTAINING 2,6,7-TRIOXA-1-PHOSPHABICYCLO(2.2.2.)OCTANE RING | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |