Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9793008 | 0.88 | MAPT (0.52) | KDM4EMAPTGAAALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9793078 | 0.86 | MAPT (0.50) | KDM4EMAPTGAAALDH1A1HSD17B10 | |
| SCHEMBL29452826 | 0.81 | IDO1 (0.48) | KDM4EMAPTGAAALDH1A1HSD17B10 | |
| SCHEMBL455551 | 0.81 | IDO1 (0.48) | KDM4EMAPTGAAALDH1A1HSD17B10 | |
| SCHEMBL27494768 | 0.79 | KDM4E (0.60) | KDM4EMAPTGAAALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL10535611 | 0.79 | EP300 (0.50) | KDM4EMAPTGAAALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9793151 | 0.79 | EP300 (0.50) | KDM4EMAPTGAAALDH1A1HSD17B10 | |
| SCHEMBL28060146 | 0.79 | MAPT (0.55) | KDM4EMAPTGAAALDH1A1HSD17B10 | |
| SCHEMBL6675123 | 0.78 | ALDH1A1 (0.53) | KDM4EMAPTGAAALDH1A1HSD17B10 | |
| SCHEMBL3426858 | 0.77 | ALDH1A1 (0.62) | KDM4EMAPTGAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705863-A1 | Two stage melt polymerization process for making polybenzimidazoles | HOECHST CELANESE CORPORATION (US) | 1996-04-10 | — | — | EP | disclosed |
| US-4895928-A | AROMATIC POLYAMIDES | AMOCO CORPORATION (US) | 1990-01-23 | — | — | US | disclosed |
| US-4717764-A | Two stage melt polymerization process for making polymers containing aromatic amide groups | CELANESE CORPORATION (US) | 1988-01-05 | — | — | US | disclosed |