SCHEMBL8975962

SCHEMBL8975962

OCc1ccc2sc(S)nc2c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.65
ILK Q13418 2/20 0.47
KDM4E B2RXH2 2/20 0.41
CA2 P00918 1/20 0.41
NPC1 O15118 5/20 0.39
RAB9A P51151 5/20 0.39
NFKB1 P19838 4/20 0.39
NFKB2 Q00653 4/20 0.39
RELA Q04206 4/20 0.39
APP P05067 2/20 0.39
HPGD P15428 2/20 0.39
STAT1 P42224 1/20 0.39
HDAC6 Q9UBN7 2/20 0.38
TRPV1 Q8NER1 3/20 0.37
DYRK1A Q13627 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
PKM P14618 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8975913 0.86 APP (0.52) HSD17B10ILKKDM4ECA2NPC1
SCHEMBL1772237 0.82 NPC1 (0.47) HSD17B10ILKKDM4ENPC1RAB9A
SCHEMBL31630242 0.80 HSD17B10 (0.67) HSD17B10ILKKDM4ECA2NPC1
SCHEMBL10358903 0.79 HSD17B10 (0.45) HSD17B10ILKKDM4ENPC1RAB9A
SCHEMBL31629892 0.79 HSD17B10 (0.65) HSD17B10ILKKDM4ECA2NPC1
SCHEMBL3436150 0.79 HSD17B10 (1.00) HSD17B10ILKNPC1RAB9AAPP
SCHEMBL18364999 0.79 HSD17B10 (0.65) HSD17B10ILKCA2NPC1RAB9A
SCHEMBL7648815 0.77 HSD17B10 (0.43) HSD17B10NPC1RAB9ANFKB1NFKB2
SCHEMBL3046846 0.76 CA2 (0.53) HSD17B10ILKKDM4ECA2NPC1
SCHEMBL1094971 0.75 NPC1 (0.35) HSD17B10KDM4ECA2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240230952-A1 LAMINATE AND METHOD FOR MANUFACTURING LAMINATE FUJIFILM CORPORATION (JP) 2024-07-11 US disclosed
US-20240027897-A1 LAMINATE AND MANUFACTURING METHOD OF LAMINATE FUJIFILM CORPORATION (JP) 2024-01-25 US disclosed
US-9274422-B2 Photosensitive resin composition, method for forming pattern-cured film using photosensitive resin composition, and electronic component HITACHI CHEMICAL DUPONT MICROSYSTEMS, LTD. (JP) 2016-03-01 US disclosed
US-20140120462-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR FORMING PATTERN-CURED FILM USING PHOTOSENSITIVE RESIN COMPOSITION, AND ELECTRONIC COMPONENT HITACHI CHEMICAL DUPONT MICROSYSTEMS, LTD. (JP) 2014-05-01 US disclosed
US-5565445-A ANTIBIOTICS, USEFUL AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS OR STAPHYLOCOCCUS EPIDERMIDIS AND METHICILLIN RESITANT COAGULASE NEGATIVE STAPHYLOCOCCI MERCK & CO., INC. (US) 1996-10-15 US disclosed
US-5541176-A ANTIBIOTICS, USEFUL AGAINST METHICILLIN RESISTANT STAPHYLOCOCCUS MERCK & CO., INC. (US) 1996-07-30 US disclosed
US-5538964-A ANTIBIOTICS FOR BACTERICIDES MERCK & CO., INC. (US) 1996-07-23 US disclosed
US-5498777-A 3-thioheteroaryl cephalosporin compounds, compositions and methods of use MERCK & CO., INC. (US) 1996-03-12 US disclosed
WO-1996002548-A1 3-THIOHETEROARYL CEPHALOSPORIN COMPOUNDS, COMPOSITIONS AND METHODS OF USE MERCK & CO., INC. (US) 1996-02-01 WO disclosed