Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4577656 | 0.79 | USP2 (0.41) | TSHRUSP2CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL4577660 | 0.79 | KMT2A (0.52) | TSHRUSP2CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL14077043 | 0.79 | KMT2A (0.43) | TSHRUSP2HDAC3HDAC4HDAC1 | |
| SCHEMBL8956632 | 0.78 | USP2 (0.40) | TSHRUSP2CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL3332159 | 0.77 | MEN1 (0.55) | TSHRUSP2HDAC3HDAC4HDAC1 | |
| SCHEMBL18573074 | 0.76 | ECE1 (0.53) | TSHRUSP2CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL9509585 | 0.75 | TERT (0.39) | TSHRUSP2HDAC3HDAC4HDAC1 | |
| SCHEMBL10490843 | 0.75 | TERT (0.39) | TSHRUSP2HDAC3HDAC4HDAC1 | |
| SCHEMBL8956643 | 0.74 | USP2 (0.38) | TSHRUSP2CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL10304548 | 0.73 | EPHX1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514282-B1 | Alkylamino mercaptoalkylamides or salts thereof acceptable for cosmetic use, their use as a reducing agent and a process for the permanent deformation of hair | OREAL (FR) | 1996-04-10 | — | — | EP | claimed |