Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 2/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29865552 | 0.80 | BAZ2B (0.56) | BAZ2BPOLBTSPOLMNAELANE | |
| SCHEMBL14717080 | 0.80 | BAZ2B (0.56) | BAZ2BPOLBTSPOLMNAELANE | |
| SCHEMBL9983145 | 0.79 | POLB (0.70) | BAZ2BNPC1RAB9AL3MBTL1POLB | |
| SCHEMBL8976235 | 0.78 | FEN1 (0.42) | TSPODDB1CRBNKDM4EMAPT | |
| SCHEMBL17339010 | 0.74 | FEN1 (0.46) | L3MBTL1DDB1CRBNKDM4EPDE4A | |
| SCHEMBL12166069 | 0.74 | MYC (0.45) | L3MBTL1POLBLMNAELANEKDM4E | |
| SCHEMBL17105722 | 0.73 | MEN1 (0.38) | DDB1CRBNLMNAKDM4EMAPT | |
| SCHEMBL14253011 | 0.73 | BAZ2B (0.45) | BAZ2BNPC1RAB9APOLBTSPO | |
| SCHEMBL675512 | 0.72 | PTGDR2 (0.48) | LMNAMAPTALDH1A1 | |
| SCHEMBL12166116 | 0.71 | HSD17B10 (0.44) | L3MBTL1LMNAELANEKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532261-A | TREATING STAPHYLOCOCCUS INFECTIONS | MERCK & CO., INC. (US) | 1996-07-02 | — | — | US | disclosed |