Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34006 | 0.84 | TDP1 (0.58) | TDP1ATMBCHEKDM4EALDH1A1 | |
| SCHEMBL30438185 | 0.84 | TDP1 (0.58) | TDP1ATMBCHEKDM4EALDH1A1 | |
| SCHEMBL10627807 | 0.81 | TDP1 (0.55) | TDP1ATMBCHEKDM4EALDH1A1 | |
| SCHEMBL30134334 | 0.81 | TDP1 (0.62) | TDP1ATMBCHEKDM4EALDH1A1 | |
| SCHEMBL27853484 | 0.81 | TDP1 (0.72) | TDP1ATMBCHEKDM4EALDH1A1 | |
| SCHEMBL47807 | 0.81 | TDP1 (0.62) | TDP1ATMBCHEKDM4EALDH1A1 | |
| SCHEMBL47808 | 0.79 | TDP1 (0.65) | TDP1ATMBCHEKDM4EALDH1A1 | |
| SCHEMBL1789658 | 0.79 | TDP1 (0.60) | TDP1ATMBCHEKDM4EALDH1A1 | |
| SCHEMBL31304747 | 0.79 | TDP1 (0.65) | TDP1ATMBCHEKDM4EALDH1A1 | |
| SCHEMBL6403938 | 0.79 | TDP1 (0.60) | TDP1ATMBCHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489647-A | ABSORBERS FOR WATER AND AQUEOUS SOLUTIONS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-02-06 | — | — | US | disclosed |
| US-5011892-A | Polyether and addition polymer | CASSELLA AG (DE) | 1991-04-30 | — | — | US | disclosed |