SCHEMBL30438185

SCHEMBL30438185

C=CC(=O)Oc1ccccc1C(C)(C)C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.58
ATM Q13315 1/20 0.58
THRB P10828 2/20 0.49
THRA P10827 1/20 0.49
BCHE P06276 1/20 0.48
KDM4E B2RXH2 4/20 0.43
ALDH1A1 P00352 4/20 0.43
GAA P10253 2/20 0.43
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
RXRG P48443 1/20 0.43
NPSR1 Q6W5P4 1/20 0.40
NAMPT P43490 1/20 0.40
RBP4 P02753 4/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TSHR P16473 1/20 0.38
ELANE P08246 1/20 0.38
TYMS P04818 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34006 1.00 TDP1 (0.58) TDP1ATMTHRBTHRABCHE
SCHEMBL1833758 0.90 THRB (0.49) TDP1ATMTHRBTHRABCHE
SCHEMBL27745677 0.85 CA2 (0.48) TDP1ATMTHRBTHRABCHE
SCHEMBL21596952 0.85 TDP1 (0.43) TDP1ATMTHRBTHRABCHE
Hydrochloric Acid SCHEMBL17698428 0.85 THRB (0.46) TDP1ATMTHRBTHRABCHE
SCHEMBL8976180 0.84 TDP1 (0.55) TDP1ATMBCHEKDM4EALDH1A1
SCHEMBL25367674 0.84 THRB (0.51) TDP1ATMTHRBTHRABCHE
SCHEMBL10883978 0.84 ATM (0.46) TDP1ATMTHRBTHRABCHE
SCHEMBL28818569 0.83 THRB (0.44) TDP1ATMTHRBTHRABCHE
SCHEMBL4230062 0.83 ATM (0.41) TDP1ATMTHRBTHRABCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3083865-B1 PROCESS FOR PRODUCING CROSSLINKED POLYMERS TESA SE (DE) 2025-04-02 EP disclosed
EP-4486807-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION TESA SE (DE) 2025-01-08 EP disclosed
EP-2832811-B1 Adhesive mass TESA SE (DE) 2024-03-20 EP disclosed
WO-2023165966-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION TESA SE (DE) 2023-09-07 WO disclosed
WO-2023094549-A1 FLEXIBLE PRESSURE-SENSITIVE ADHESIVES HAVING IMPROVED PROPERTIES WESTFÄLISCHE HOCHSCHULE GELSENKIRCHEN BOCHOLT RECKLINGHAUSEN (DE) 2023-06-01 WO disclosed