SCHEMBL8976204

SCHEMBL8976204

Cc1c(C(=O)O)c(O)cc2c1C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 8/20 0.49
MAPT P10636 8/20 0.49
KMT2A Q03164 8/20 0.49
KDM4E B2RXH2 7/20 0.49
CYP3A4 P08684 6/20 0.49
ALDH1A1 P00352 6/20 0.49
RECQL P46063 6/20 0.49
HSD17B10 Q99714 5/20 0.49
TDP1 Q9NUW8 5/20 0.49
MAPK1 P28482 5/20 0.49
HPGD P15428 4/20 0.49
APEX1 P27695 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
MMP14 P50281 1/20 0.49
PTPN1 P18031 1/20 0.49
SLC37A4 O43826 1/20 0.49
JUN P05412 1/20 0.48
USP2 O75604 4/20 0.43
THRB P10828 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29359752 0.86 MEN1 (0.52) MEN1MAPTKMT2AKDM4ECYP3A4
SCHEMBL33762 0.86 MEN1 (0.52) MEN1MAPTKMT2AKDM4ECYP3A4
SCHEMBL18551446 0.86 MEN1 (0.52) MEN1MAPTKMT2AKDM4ECYP3A4
SCHEMBL29470044 0.86 MEN1 (0.52) MEN1MAPTKMT2AKDM4ECYP3A4
SCHEMBL30848230 0.85 SLC37A4 (0.67) MEN1MAPTKMT2AKDM4ECYP3A4
SCHEMBL5142787 0.85 SLC37A4 (0.67) MEN1MAPTKMT2AKDM4ECYP3A4
SCHEMBL8976457 0.83 MAPT (0.55) MEN1MAPTKMT2AKDM4ECYP3A4
SCHEMBL2138871 0.81 CYP3A4 (0.60) MEN1MAPTKMT2AKDM4ECYP3A4
SCHEMBL29356605 0.81 CYP3A4 (0.60) MEN1MAPTKMT2AKDM4ECYP3A4
SCHEMBL28128464 0.78 MAPT (0.48) MEN1MAPTKMT2AKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0602027-B1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES EUROP COLOUR PLC (GB) 1996-03-27 EP claimed
US-5424421-A Synthesis of carminic acid and principal intermediates EUROPEAN COLOUR PLC (GB) 1995-06-13 US claimed
EP-0602027-A1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES. EUROP COLOUR PLC (GB) 1994-06-22 EP claimed
WO-1992001664-A1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES EUROPEAN COLOUR PLC (GB) 1992-02-06 WO claimed
EP-0602027-B1 SYNTHESIS OF CARMINIC ACID AND PRINCIPAL INTERMEDIATES EUROP COLOUR PLC (GB) 1996-03-27 EP disclosed
US-5424421-A Synthesis of carminic acid and principal intermediates EUROPEAN COLOUR PLC (GB) 1995-06-13 US disclosed