Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL699498 | 0.78 | EPHX1 (0.44) | ALDH1A1HSD17B10ACHEEPHX1MEN1 | |
| SCHEMBL10257689 | 0.76 | MEN1 (0.49) | ALDH1A1HSD17B10ACHEEPHX1MEN1 | |
| SCHEMBL6259653 | 0.75 | MAPT (0.44) | ALDH1A1HSD17B10ACHEEPHX1MEN1 | |
| SCHEMBL11693135 | 0.74 | EPHX1 (0.61) | ALDH1A1HSD17B10ACHEEPHX1MEN1 | |
| SCHEMBL22567 | 0.74 | ALDH1A1 (0.72) | ALDH1A1HSD17B10ACHEMEN1KMT2A | |
| SCHEMBL27909482 | 0.74 | ALDH1A1 (0.72) | ALDH1A1HSD17B10ACHEMEN1KMT2A | |
| SCHEMBL6175110 | 0.73 | KMT2A (0.46) | ALDH1A1HSD17B10ACHEEPHX1MEN1 | |
| SCHEMBL29492618 | 0.72 | EPHX1 (0.40) | ALDH1A1HSD17B10ACHEEPHX1MEN1 | |
| SCHEMBL9636565 | 0.72 | SMN1; SMN2 (0.53) | ALDH1A1HSD17B10ACHEEPHX1MEN1 | |
| Hydrogen Sulfide SCHEMBL27319417 | 0.71 | ALDH1A1 (0.68) | ALDH1A1HSD17B10ACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537518-B1 | Derivatives of 2,2-dihalobenzo(1,3)dioxoles substituted in the 4-position, methods for their preparation and their use | BAYER AG (DE) | 1996-04-17 | — | — | EP | disclosed |
| US-5281725-A | Derivatives of 2,2-dihalogenobenzo[1,3]dioxoles substituted in the 4-position, processes for their preparation and their use | BAYER AKTIENGESELLSCHAFT (DE) | 1994-01-25 | — | — | US | disclosed |
| EP-0537518-A1 | Derivatives of 2,2-dihalobenzo(1,3)dioxoles substituted in the 4-position, methods for their preparation and their use | BAYER AG (DE) | 1993-04-21 | — | — | EP | disclosed |