Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4603241 | 0.98 | MEN1 (0.59) | MEN1KMT2ASLC6A4LTA4HCYP1A2 | |
| SCHEMBL4603238 | 0.98 | MEN1 (0.59) | MEN1KMT2ASLC6A4LTA4HCYP1A2 | |
| Ammonia Solution, Strong SCHEMBL5305768 | 0.93 | ALDH1A1 (0.58) | MEN1KMT2ASLC6A4LTA4HCYP1A2 | |
| SCHEMBL28344007 | 0.91 | ALDH1A1 (0.59) | MEN1KMT2ASLC6A4LTA4HCYP1A2 | |
| SCHEMBL28344005 | 0.91 | ALDH1A1 (0.59) | MEN1KMT2ASLC6A4LTA4HCYP1A2 | |
| SCHEMBL10338355 | 0.89 | CYP1A2 (0.63) | MEN1KMT2ASLC6A4LTA4HCYP1A2 | |
| Fumaric Acid SCHEMBL8867436 | 0.88 | TDP1 (0.53) | MEN1KMT2ALDHAALDH1A1PPARG | |
| SCHEMBL9069704 | 0.84 | ESR1 (0.61) | SLC6A4SIGMAR1ESR1ESR2 | |
| SCHEMBL21286388 | 0.84 | CYP1A2 (0.58) | MEN1KMT2ASLC6A4CYP1A2CYP2D6 | |
| SCHEMBL217345 | 0.83 | MEN1 (0.62) | MEN1KMT2ASLC6A4LTA4HCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539120-A | Arylalkyl-amines having anticonvulsant and neuroprotective properties | AGENCE SPATIALE EUROPEENNE (FR) | 1996-07-23 | — | — | US | claimed |
| EP-0356035-B1 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | ASTRA AB (SE) | 1996-03-13 | — | — | EP | claimed |
| WO-1991011995-A1 | ARYLALKYL-AMINES AND -AMIDES HAVING ANTICONVULSANT AND NEUROPROTECTIVE PROPERTIES | FISONS CORPORATION (US) | 1991-08-22 | — | — | WO | claimed |
| EP-0356035-A2 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | Astra Aktiebolag (SE) | 1990-02-28 | — | — | EP | claimed |