SCHEMBL897666

SCHEMBL897666

CC(C)(C)C(C(=O)O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
MAPT P10636 1/20 0.39
PTGS1 P23219 1/20 0.39
TSHR P16473 2/20 0.39
TP53 P04637 1/20 0.39
SLC7A5 Q01650 1/20 0.38
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.33
RECQL P46063 1/20 0.33
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
ABCB11 O95342 1/20 0.32
F2 P00734 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8110260 0.97 ALDH1A1 (0.38) ALDH1A1MAPTPTGS1TSHRTP53
Magnesium SCHEMBL7958509 0.97 ALDH1A1 (0.38) ALDH1A1MAPTPTGS1TSHRTP53
Magnesium SCHEMBL29455973 0.97 ALDH1A1 (0.38) ALDH1A1MAPTPTGS1TSHRTP53
SCHEMBL28315607 0.97 ALDH1A1 (0.38) ALDH1A1MAPTPTGS1TSHRTP53
Methyl Alcohol SCHEMBL28215181 0.97 ALDH1A1 (0.38) ALDH1A1MAPTPTGS1TSHRTP53
SCHEMBL28314602 0.97 ALDH1A1 (0.38) ALDH1A1MAPTPTGS1TSHRTP53
SCHEMBL21268936 0.97 ALDH1A1 (0.38) ALDH1A1MAPTPTGS1TSHRTP53
SCHEMBL21269999 0.97 ALDH1A1 (0.38) ALDH1A1MAPTPTGS1TSHRTP53
SCHEMBL21269846 0.97 ALDH1A1 (0.38) ALDH1A1MAPTPTGS1TSHRTP53
SCHEMBL28315786 0.94 ALDH1A1 (0.36) ALDH1A1MAPTPTGS1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1754747-B1 PHOTOINITIATOR COMPOSITION INCLUDING HINDERED AMINE STABILIZER BLUESTAR SILICONES FRANCE (FR) 2015-02-25 EP claimed
EP-1754747-A1 Photoinitiator composition including hindered amine stabilizer RHODIA INC. (US) 2007-02-21 EP claimed
EP-1045879-A1 PHOTOINITIATOR COMPOSITION INCLUDING HINDERED AMINE STABILIZER RHODIA INC. (US) 2000-10-25 EP claimed
US-5973020-A COMPRISING COMPOSITION WHICH YIELDS CATIONS UPON EXPOSURE TO ACTINIC RADIATION AND STABILIZING AMINO AGENT; PARTICULARLY USEFUL FOR SILOXANE POLYMERIZATION WHEN EXPOSED TO ULTRAVIOLET RADIATION RHODIA INC. (US) 1999-10-26 US claimed
WO-1999035188-A1 PHOTOINITIATOR COMPOSITION INCLUDING HINDERED AMINE STABILIZER RHODIA INC. (US) 1999-07-15 WO claimed
US-5831119-A Process for the preparation of aminoacetic acids with a tertiary hydrocarbon radical in the α-position, or their nitriles HUELS AKTIENGESELLSCHAFT (DE) 1998-11-03 US claimed
JP-10059908-A None JP disclosed
US-20230142119-A1 TETRACYCLIC COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2023-05-11 US disclosed
US-20220306578-A1 TETRACYCLIC COMPOUND CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2022-09-29 US disclosed
CN-110172019-B Metal salts of malonic acid as nucleating additives for crystalline thermoplastics 印度石油有限公司 2022-03-04 CN disclosed
CN-110790896-B Blocked polyisocyanate and aqueous coating composition containing same KCC公司 2022-01-28 CN disclosed
EP-3613729-A1 TETRACYCLIC COMPOUNDS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2020-02-26 EP disclosed
CN-110790896-A Blocked polyisocyanate and aqueous coating composition containing same KCC公司 2020-02-14 CN disclosed
EP-0379314-A1 3-(1,2,5,6-Tetrahydropyridyl)-pyrrolopyridines PFIZER INC. (US) 1990-07-25 EP disclosed
US-4886614-A DIESTER OF CYCLOHEXANE TOA NENRYO KOGYO, K.K. (JP) 1989-12-12 US disclosed
EP-0330172-A2 Improved process for trans-6-[2-(substituted-pyrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis WARNER-LAMBERT COMPANY (US) 1989-08-30 EP disclosed
EP-0319580-A1 TRACTION FLUID Tonen Corporation (JP) 1989-06-14 EP disclosed
EP-0275480-A2 Renin inhibitors IV WARNER-LAMBERT COMPANY (US) 1988-07-27 EP disclosed
EP-0224088-A2 Process for the solid-phase synthesis of retro-inverso peptides ENIRICERCHE S.p.A. (IT) 1987-06-03 EP disclosed
EP-0129105-B1 PROCESS FOR PREPARING HARDENING AGENTS FOR PAINT BINDERS Vianova Kunstharz Aktiengesellschaft (AT) 1987-01-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230142119-A1 TETRACYCLIC COMPOUND ALK, TTR, ACVR1 ALDH1A1 1165/4885MAPT 68/4885PTGS1 4228/4885
US-20220306578-A1 TETRACYCLIC COMPOUND ALK, TTR, ACVR1 ALDH1A1 1165/4885MAPT 68/4885PTGS1 4228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.