Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 2/20 | 0.32 |
| ▸ | LDHA | P00338 | 2/20 | 0.31 |
| ▸ | LDHB | P07195 | 1/20 | 0.31 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL20639246 | 0.96 | — | — | |
| Ammonia Solution, Strong SCHEMBL27991054 | 0.92 | — | — | |
| SCHEMBL7898 | 0.91 | — | — | |
| SCHEMBL7258925 | 0.91 | TSHR (0.54) | CYP1A2TSHRNFKB1MAOAMAOB | |
| Hydrazine SCHEMBL14118554 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL3403342 | 0.87 | — | — | |
| SCHEMBL28803623 | 0.87 | — | — | |
| SCHEMBL1618596 | 0.87 | — | — | |
| SCHEMBL27852089 | 0.87 | — | — | |
| Water SCHEMBL9312726 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702670-A1 | IODOPROPARGYL CARBAMATES AND THEIR USE AS BIOCIDES IN THE PROTECTION OF PLANTS AND MATERIALS | BAYER AG (DE) | 1996-03-27 | — | — | EP | disclosed |
| WO-1994029268-A1 | IODOPROPARGYL CARBAMATES AND THEIR USE AS BIOCIDES IN THE PROTECTION OF PLANTS AND MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 1994-12-22 | — | — | WO | disclosed |