SCHEMBL8976904

SCHEMBL8976904

CO[SiH](CCCCCCC1CCCC1)OC

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 4/20 0.46
CYP1A2 P05177 1/20 0.43
FKBP1A P62942 3/20 0.34
EPHX1 P07099 1/20 0.33
KDM5A P29375 3/20 0.33
PHF8 Q9UPP1 3/20 0.33
KDM2A Q9Y2K7 3/20 0.33
KDM4C Q9H3R0 2/20 0.33
KDM4A O75164 1/20 0.32
NAAA Q02083 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8160018 0.98 SIGMAR1 (0.48) SIGMAR1CYP1A2FKBP1AEPHX1KDM5A
SCHEMBL7939625 0.98 SIGMAR1 (0.48) SIGMAR1CYP1A2FKBP1AEPHX1KDM5A
SCHEMBL29239016 0.98 SIGMAR1 (0.48) SIGMAR1CYP1A2FKBP1AEPHX1KDM5A
SCHEMBL29239007 0.98 SIGMAR1 (0.48) SIGMAR1CYP1A2FKBP1AEPHX1KDM5A
SCHEMBL7625276 0.98 CYP1A2 (0.45) SIGMAR1CYP1A2FKBP1AEPHX1NAAA
SCHEMBL7938669 0.96 CYP1A2 (0.48) SIGMAR1CYP1A2FKBP1AEPHX1NAAA
SCHEMBL819915 0.92 CYP1A2 (0.46) SIGMAR1CYP1A2FKBP1AEPHX1
SCHEMBL10009769 0.90 CYP1A2 (0.50) SIGMAR1CYP1A2FKBP1AEPHX1
SCHEMBL819314 0.90 CYP1A2 (0.50) SIGMAR1CYP1A2FKBP1AEPHX1
SCHEMBL28451299 0.85 SIGMAR1 (0.32) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0702701-A1 METHOD FOR POLYMERISING OR COPOLYMERISING PROPYLENE IN LIQUID PROPYLENE, SOLID CATALYTIC COMPONENT, AND METHOD FOR MAKING SAME APPRYL S.N.C. (FR) 1996-03-27 EP disclosed
WO-1995022568-A1 METHOD FOR POLYMERISING OR COPOLYMERISING PROPYLENE IN LIQUID PROPYLENE, SOLID CATALYTIC COMPONENT, AND METHOD FOR MAKING SAME APPRYL S.N.C. (FR) 1995-08-24 WO disclosed