Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 8/20 | 0.44 |
| ▸ | CA12 | O43570 | 7/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | SORD | Q00796 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260146 | 0.82 | CA12 (0.67) | CA9CA12MAOBAKR1B1MAOA | |
| SCHEMBL7809251 | 0.82 | CA9 (0.50) | CA9CA12MAOBAKR1B1MAOA | |
| SCHEMBL7816433 | 0.82 | CA9 (0.42) | CA9CA12MAOBAKR1B1MAOA | |
| SCHEMBL30228183 | 0.80 | CA9 (0.68) | CA9CA12MAOBAKR1B1MAOA | |
| SCHEMBL2979482 | 0.80 | CA9 (0.68) | CA9CA12MAOBAKR1B1MAOA | |
| SCHEMBL9263020 | 0.79 | CA9 (0.48) | CA9CA12MAOBAKR1B1MAOA | |
| SCHEMBL9260112 | 0.79 | CA9 (0.43) | CA9CA12MAOBAKR1B1MAOA | |
| SCHEMBL2985971 | 0.78 | CA12 (0.50) | CA9CA12MAOBAKR1B1MAOA | |
| SCHEMBL7813458 | 0.78 | CA9 (0.69) | CA9CA12MAOBAKR1B1MAOA | |
| SCHEMBL7813037 | 0.77 | PIM1 (0.40) | CA9CA12MAOBAKR1B1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552437-A | ANTIASTHMATIC, ANTIALLERGIC, ANTIINFLAMMATORY, AND CYTOPROTECTIVE AGENTS | MERCK FROSST CANADA, INC. (CA) | 1996-09-03 | — | — | US | disclosed |
| US-5527827-A | ANTIASTHMATIC, ANTIALLERGIC, ANTIINFLAMMATORY AND CYTOPROTECTIVE AGENTS | MERCK FROSST CANADA, INC. (CA) | 1996-06-18 | — | — | US | disclosed |