SCHEMBL8976953

SCHEMBL8976953

CCCC(C)CCCCCCOP(=O)(O)OCCCCCCC(C)CCC

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 7/20 0.48
LPAR2 Q9HBW0 6/20 0.48
LPAR1 Q92633 3/20 0.48
SMPD1 P17405 3/20 0.41
ACE2 Q9BYF1 1/20 0.41
FDPS P14324 3/20 0.40
P2RY10 O00398 4/20 0.39
LPAR5 Q9H1C0 1/20 0.38
GPR34 Q9UPC5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8976974 0.89 LPAR3 (0.63) LPAR3LPAR2LPAR1SMPD1ACE2
SCHEMBL8976939 0.88 LPAR3 (0.61) LPAR3LPAR2LPAR1SMPD1ACE2
SCHEMBL11428437 0.85 LPAR3 (0.42) LPAR3LPAR2LPAR1SMPD1FDPS
SCHEMBL8858256 0.85 FDPS (0.41) LPAR3LPAR2LPAR1SMPD1FDPS
SCHEMBL28359503 0.84 LPAR3 (0.43) LPAR3LPAR2LPAR1SMPD1FDPS
SCHEMBL25372060 0.82 LPAR3 (0.58) LPAR3LPAR2LPAR1SMPD1FDPS
SCHEMBL1099373 0.82 LPAR3 (0.58) LPAR3LPAR2LPAR1SMPD1FDPS
SCHEMBL10661398 0.82 LPAR3 (0.75) LPAR3LPAR2LPAR1SMPD1ACE2
SCHEMBL29164984 0.82 LPAR3 (0.58) LPAR3LPAR2LPAR1SMPD1FDPS
Hexane SCHEMBL28355564 0.82 LPAR3 (0.58) LPAR3LPAR2LPAR1SMPD1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0442701-B1 Topical composition UNILEVER PLC (GB) 1996-04-24 EP claimed
US-5139781-A And a cationic cellulose polymer to enhance mildness; for applying to hair or skin CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1992-08-18 US claimed
EP-0442701-A2 Topical composition UNILEVER PLC (GB) 1991-08-21 EP claimed
EP-0442701-B1 Topical composition UNILEVER PLC (GB) 1996-04-24 EP disclosed
US-5139781-A And a cationic cellulose polymer to enhance mildness; for applying to hair or skin CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1992-08-18 US disclosed
EP-0442701-A2 Topical composition UNILEVER PLC (GB) 1991-08-21 EP disclosed