Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.56 |
| ▸ | MEN1 | O00255 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977114 | 0.89 | MAPT (0.64) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL8940873 | 0.78 | KMT2A (0.63) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL28158296 | 0.78 | KMT2A (0.70) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL23041342 | 0.76 | MAPT (0.55) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL5215487 | 0.76 | MAPT (0.58) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL4740981 | 0.75 | MEN1 (0.54) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL27676843 | 0.75 | MEN1 (0.74) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL12111929 | 0.75 | MAPT (0.54) | KMT2AMEN1MAPTALDH1A1NPC1 | |
| SCHEMBL5222845 | 0.75 | MAPT (0.63) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL4255958 | 0.75 | MAPT (0.66) | KMT2AMEN1MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0517871-B1 | NOVEL NITROANILIDES AND THEIR PREPARATION | KODAK LTD (GB) | 1996-04-24 | — | — | EP | disclosed |
| US-5382682-A | Nitroanilides and their preparation | EASTMAN KODAK COMPANY (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0517871-A1 | NOVEL NITROANILIDES AND THEIR PREPARATION. | KODAK LTD (GB) | 1992-12-16 | — | — | EP | disclosed |
| WO-1992011230-A1 | NOVEL NITROANILIDES AND THEIR PREPARATION | KODAK LIMITED (GB) | 1992-07-09 | — | — | WO | disclosed |