Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CTSV | O60911 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MYOC | Q99972 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 3/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5170350 | 0.94 | MEN1 (0.48) | MEN1KMT2APKMGAACTSV | |
| SCHEMBL28844748 | 0.86 | KMT2A (0.73) | MEN1KMT2APKMGAAMAPT | |
| SCHEMBL4232458 | 0.84 | CYP17A1 (0.41) | MEN1KMT2APKMGAAMMP1 | |
| SCHEMBL4743512 | 0.82 | HPGD (0.41) | MEN1KMT2AGAAMAPTNPC1 | |
| SCHEMBL1532248 | 0.79 | KMT2A (0.59) | MEN1KMT2AGAAMAPTNPC1 | |
| SCHEMBL6590677 | 0.79 | CTSV (0.67) | MEN1KMT2APKMGAACTSV | |
| SCHEMBL4683961 | 0.77 | MAPK1 (0.41) | MEN1KMT2AMAPTNPSR1MAPK1 | |
| SCHEMBL29130752 | 0.77 | AKR1C3 (0.43) | MEN1KMT2AGAAMAPTAKR1C3 | |
| SCHEMBL5214063 | 0.77 | MAPT (0.57) | MEN1KMT2AGAACTSVCTSL | |
| SCHEMBL29730718 | 0.77 | MEN1 (0.57) | MEN1KMT2AMAPTNPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |