Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 9/20 | 0.62 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.62 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.62 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.62 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.62 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.62 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.51 |
| ▸ | PRKCG | P05129 | 2/20 | 0.51 |
| ▸ | PRKCB | P05771 | 2/20 | 0.51 |
| ▸ | PRKCA | P17252 | 2/20 | 0.51 |
| ▸ | PRKCH | P24723 | 2/20 | 0.51 |
| ▸ | PRKCI | P41743 | 2/20 | 0.51 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.51 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.51 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.51 |
| ▸ | AKT1 | P31749 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059626 | 0.84 | LPAR1 (0.59) | LPAR1LPAR3LPAR5LPAR2LPAR6 | |
| SCHEMBL8933348 | 0.84 | LPAR1 (0.59) | LPAR1LPAR3LPAR5LPAR2LPAR6 | |
| SCHEMBL5610918 | 0.83 | LPAR3 (0.79) | LPAR1LPAR3LPAR5LPAR2LPAR6 | |
| SCHEMBL7172379 | 0.83 | LPAR3 (0.79) | LPAR1LPAR3LPAR5LPAR2LPAR6 | |
| SCHEMBL5610920 | 0.83 | LPAR3 (0.79) | LPAR1LPAR3LPAR5LPAR2LPAR6 | |
| SCHEMBL3217259 | 0.83 | LPAR3 (0.79) | LPAR1LPAR3LPAR5LPAR2LPAR6 | |
| SCHEMBL10566328 | 0.82 | LPAR3 (0.68) | LPAR1LPAR3LPAR5LPAR2LPAR6 | |
| SCHEMBL11100467 | 0.81 | LPAR1 (0.68) | LPAR1LPAR3LPAR5LPAR2LPAR6 | |
| SCHEMBL10409567 | 0.81 | LPAR1 (0.68) | LPAR1LPAR3LPAR5LPAR2LPAR6 | |
| SCHEMBL11102642 | 0.81 | LPAR1 (0.68) | LPAR1LPAR3LPAR5LPAR2LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512671-A | VIRICIDES | WAKE FOREST UNIVERSITY (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0533825-B1 | ETHER LIPID-NUCLEOSIDE COVALENT CONJUGATES | UNIV WAKE FOREST (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1991019726-A1 | ETHER LIPID-NUCLEOSIDE COVALENT CONJUGATES | WAKE FOREST UNIVERSITY (US) | 1991-12-26 | — | — | WO | disclosed |