Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93783 | 0.84 | — | — | |
| SCHEMBL28831589 | 0.82 | MAOA (0.54) | MAOAMAOBKMT2ACYP1A2LMNA | |
| Hydrochloric Acid SCHEMBL16227633 | 0.82 | MAOA (0.54) | MAOAMAOBKMT2ACYP1A2LMNA | |
| SCHEMBL6804776 | 0.81 | CYP1A2 (0.52) | MAOAMAOBKMT2ACYP1A2LMNA | |
| SCHEMBL7984820 | 0.79 | CYP1A2 (0.56) | MAOAMAOBKMT2ACYP1A2LMNA | |
| SCHEMBL163406 | 0.78 | MAOA (0.65) | MAOAMAOBKMT2ACYP1A2LMNA | |
| SCHEMBL162148 | 0.78 | — | — | |
| SCHEMBL181523 | 0.77 | MAOA (0.69) | MAOAMAOBKMT2ACYP1A2LMNA | |
| SCHEMBL288829 | 0.77 | MAOA (0.69) | MAOAMAOBKMT2ACYP1A2LMNA | |
| SCHEMBL11113096 | 0.77 | MAOA (0.63) | MAOAMAOBKMT2ACYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536853-A | Opiate receptor ligands | CHIRON CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |