Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL432610 | 0.88 | NAAA (0.53) | NAAAHTR2CFAAHLTA4HRAD52 | |
| SCHEMBL9062762 | 0.82 | NAAA (0.49) | NAAAHTR2CFAAHLTA4HTLR2 | |
| SCHEMBL11221404 | 0.82 | NAAA (0.56) | NAAAHTR2CFAAHRAD52NPSR1 | |
| SCHEMBL11232005 | 0.82 | NAAA (0.56) | NAAAHTR2CFAAHRAD52NPSR1 | |
| SCHEMBL11227515 | 0.82 | NAAA (0.56) | NAAAHTR2CFAAHRAD52NPSR1 | |
| SCHEMBL8927695 | 0.82 | HTR2C (0.39) | NAAAHTR2CEPHX2FAAHLTA4H | |
| SCHEMBL5497225 | 0.81 | NAAA (0.58) | NAAAHTR2CEPHX2FAAHTLR2 | |
| SCHEMBL11184933 | 0.81 | NAAA (0.58) | NAAAHTR2CEPHX2FAAHTLR2 | |
| SCHEMBL11198736 | 0.79 | NAAA (0.55) | NAAAHTR2CEPHX2FAAHTLR2 | |
| SCHEMBL6684492 | 0.79 | NAAA (0.60) | NAAAHTR2CFAAHLTA4HRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536853-A | Opiate receptor ligands | CHIRON CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |