Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977226 | 0.83 | SLC6A3 (0.60) | SLC6A3SLC6A4SLC6A2S1PR1S1PR3 | |
| SCHEMBL14944314 | 0.78 | SLC6A3 (0.59) | SLC6A3SLC6A4SLC6A2HSD11B1S1PR1 | |
| SCHEMBL12002387 | 0.77 | SLC6A3 (0.62) | SLC6A3SLC6A4SLC6A2HSD11B1S1PR1 | |
| SCHEMBL14944312 | 0.75 | SLC6A3 (0.59) | SLC6A3SLC6A4SLC6A2HSD11B1S1PR1 | |
| SCHEMBL12002389 | 0.75 | SLC6A3 (0.59) | SLC6A3SLC6A4SLC6A2HSD11B1S1PR1 | |
| SCHEMBL12000551 | 0.73 | SLC6A3 (0.57) | SLC6A3SLC6A4SLC6A2HSD11B1S1PR1 | |
| SCHEMBL12000464 | 0.73 | SLC6A3 (0.57) | SLC6A3SLC6A4SLC6A2HSD11B1S1PR1 | |
| SCHEMBL28984515 | 0.73 | SLC6A3 (0.61) | SLC6A3SLC6A4SLC6A2HSD11B1 | |
| SCHEMBL3518807 | 0.73 | SLC6A3 (1.00) | SLC6A3SLC6A4SLC6A2HSD11B1 | |
| SCHEMBL31441138 | 0.73 | SLC6A3 (1.00) | SLC6A3SLC6A4SLC6A2HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523439-A | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0696592-A1 | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |