Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP5 | P45974 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977339 | 1.00 | USP5 (0.34) | USP5HDAC6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8977338 | 0.89 | NPC1 (0.38) | KDM1A | |
| SCHEMBL8977348 | 0.89 | NPC1 (0.38) | KDM1A | |
| SCHEMBL17827776 | 0.81 | HTR2A (0.42) | USP5HDAC6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8977390 | 0.79 | USP5 (0.34) | USP5HDAC6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8977394 | 0.79 | USP5 (0.34) | USP5HDAC6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8027949 | 0.78 | USP5 (0.31) | USP5HDAC6SLC6A4 | |
| SCHEMBL8027948 | 0.78 | USP5 (0.31) | USP5HDAC6SLC6A4 | |
| SCHEMBL8027953 | 0.78 | USP5 (0.31) | USP5HDAC6SLC6A4 | |
| SCHEMBL8767567 | 0.76 | HTR2A (0.39) | USP5HDAC6HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523439-A | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0696592-A1 | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |