Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 6/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.30 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977348 | 1.00 | NPC1 (0.38) | NPC1RAB9AP2RY14DGAT1KDM4E | |
| SCHEMBL8977339 | 0.89 | USP5 (0.34) | KDM1A | |
| SCHEMBL8977347 | 0.89 | USP5 (0.34) | KDM1A | |
| SCHEMBL8944805 | 0.83 | NPC1 (0.33) | NPC1RAB9AKDM4E | |
| SCHEMBL8944808 | 0.83 | NPC1 (0.33) | NPC1RAB9AKDM4E | |
| SCHEMBL8944803 | 0.83 | NPC1 (0.33) | NPC1RAB9AKDM4E | |
| SCHEMBL8768421 | 0.79 | PGR (0.39) | NPC1RAB9AP2RY14KDM4EKDM1A | |
| SCHEMBL8768418 | 0.79 | PGR (0.39) | NPC1RAB9AP2RY14KDM4EKDM1A | |
| SCHEMBL19850903 | 0.78 | KMT2A (0.39) | NPC1RAB9AP2RY14KDM1ACYP11B1 | |
| SCHEMBL8977320 | 0.78 | NPC1 (0.41) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523439-A | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0696592-A1 | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |