Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.70 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | CRHBP | P24387 | 2/20 | 0.67 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11342106 | 0.88 | MEN1 (0.68) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL623563 | 0.86 | MEN1 (0.65) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL11335718 | 0.83 | KMT2A (0.63) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL11143572 | 0.82 | KMT2A (0.64) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL10024453 | 0.80 | MEN1 (0.65) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL9311420 | 0.80 | CXCR2 (0.59) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL622250 | 0.80 | MAPT (0.47) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL27976139 | 0.79 | SMN1; SMN2 (0.68) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL25438610 | 0.79 | MEN1 (0.64) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| Oxalic Acid SCHEMBL20984422 | 0.79 | MEN1 (0.65) | MEN1KMT2AMAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587509-A | Caged caboxyl compounds and use thereof | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-12-24 | — | — | US | disclosed |
| US-5430175-A | Caged carboxyl compounds and use thereof | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-07-04 | — | — | US | disclosed |
| WO-1995015305-A1 | CAGED CARVOXYL COMPOUNDS AND THEIR USE IN CHEMICAL KINETIC INVESTIGATION OF NEUROTRANSMITTER RECEPTORS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-06-08 | — | — | WO | disclosed |