Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | CRHBP | P24387 | 2/20 | 0.65 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977452 | 0.86 | MEN1 (0.70) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL9404796 | 0.86 | MAPT (0.63) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL11143572 | 0.85 | KMT2A (0.64) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL10024453 | 0.83 | MEN1 (0.65) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL25438610 | 0.82 | MEN1 (0.64) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL2234808 | 0.82 | KAT2B (0.63) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL13593373 | 0.80 | KMT2A (0.68) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11342106 | 0.80 | MEN1 (0.68) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL7448185 | 0.80 | MEN1 (0.61) | MEN1KMT2AMAPTSMN1; SMN2HTT | |
| SCHEMBL1520429 | 0.79 | TDP1 (0.72) | KMT2AMAPTSMN1; SMN2GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9732382-B2 | Photodamage mitigation compounds and systems | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-9732382-B2 | Photodamage mitigation compounds and systems | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-9732382-B2 | Photodamage mitigation compounds and systems | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2017-08-15 | — | — | US | disclosed |
| US-20150079603-A1 | PHOTODAMAGE MITIGATION COMPOUNDS AND SYSTEMS | PACIFIC BIOSCIENCES CALIFORNIA (US) | 2015-03-19 | — | — | US | disclosed |
| US-20150079603-A1 | PHOTODAMAGE MITIGATION COMPOUNDS AND SYSTEMS | PACIFIC BIOSCIENCES CALIFORNIA (US) | 2015-03-19 | — | — | US | disclosed |
| US-8834847-B2 | Photodamage mitigation compounds and systems | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-8834847-B2 | Photodamage mitigation compounds and systems | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-20120052488-A1 | PHOTODAMAGE MITIGATION COMPOUNDS AND SYSTEMS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120052488-A1 | PHOTODAMAGE MITIGATION COMPOUNDS AND SYSTEMS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120052488-A1 | PHOTODAMAGE MITIGATION COMPOUNDS AND SYSTEMS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| WO-2012021733-A2 | PHOTODAMAGE MITIGATION COMPOUNDS AND SYSTEMS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
| EP-0296597-B1 | Hexa-cyclic compound | DAIICHI SEIYAKU CO (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5061795-A | ANTITUMOR AGENTS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1991-10-29 | — | — | US | disclosed |
| US-4939255-A | Hexa-cyclic camptothecin derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1990-07-03 | — | — | US | disclosed |
| EP-0296597-A2 | Hexa-cyclic compound | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1988-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052488-A1 | PHOTODAMAGE MITIGATION COMPOUNDS AND SYSTEMS | CRY1, ERCC1, ERCC4 | MEN1 3583/4885KMT2A 2469/4885MAPT 518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.