SCHEMBL8977819

SCHEMBL8977819

Cc1cc(C(=O)O)c(O)c([N+](=O)[O-])c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 4/20 0.69
TSHR P16473 4/20 0.49
ALDH1A1 P00352 3/20 0.47
MAPT P10636 3/20 0.46
POLB P06746 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ABCC3 O15438 1/20 0.45
ABCC4 O15439 1/20 0.45
NR1I2 O75469 1/20 0.45
ABCB11 O95342 1/20 0.45
TTR P02766 1/20 0.45
NR3C1 P04150 1/20 0.45
PGR P06401 1/20 0.45
HTR1A P08908 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
RARB P10826 1/20 0.45
COMT P21964 1/20 0.45
SLC6A2 P23975 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31392530 0.86 GPR35 (0.69) GPR35TSHRALDH1A1MAPTPOLB
SCHEMBL4132017 0.86 GPR35 (0.69) GPR35TSHRALDH1A1MAPTPOLB
SCHEMBL6830067 0.84 TSHR (0.59) GPR35TSHRALDH1A1MAPTPOLB
SCHEMBL322531 0.82 GPR35 (1.00) GPR35TSHRALDH1A1MAPTPOLB
SCHEMBL11074065 0.81 GPR35 (0.62) GPR35TSHRALDH1A1MAPTPOLB
SCHEMBL11065981 0.81 GPR35 (0.62) GPR35TSHRALDH1A1MAPTPOLB
SCHEMBL11067071 0.81 GPR35 (0.62) GPR35ALDH1A1MAPTPOLBMEN1
SCHEMBL11069356 0.81 GPR35 (0.62) GPR35TSHRALDH1A1MAPTPOLB
SCHEMBL505297 0.81 KDM4E (0.58) GPR35TSHRALDH1A1MAPTMEN1
SCHEMBL28268730 0.81 GPR35 (0.52) GPR35TSHRALDH1A1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4396462-A Method for inhibiting the formation of polymerized vinylaromatic compounds during distillative purification of vinylaromatic monomer COSDEN TECHNOLOGY, INC. (US) 1983-08-02 US claimed
US-4374000-A Method for controlling the formation of polymer accumulations during distillation of a vinylaromatic monomer COSDEN TECHNOLOGY, INC. (US) 1983-02-15 US claimed
US-4132601-A DISTILLATION IN PRESENCE OF 3-NITRO-2,5-CRESOTIC ACID OR 3-NITRO-2,5-CRESOTALDEHYDE COSDEN TECHNOLOGY, INC. (US) 1979-01-02 US claimed
US-9884937-B2 Polymer compositions and methods SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2018-02-06 US disclosed
US-9834710-B2 Adhesive compositions and methods SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-12-05 US disclosed
US-20170022319-A1 ALIPHATIC POLYCARBONATE POLYOL COMPOSITIONS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2017-01-26 US disclosed
US-9512259-B2 High strength polyurethane foam compositions and methods NOVOMER, INC. (US) 2016-12-06 US disclosed
US-20160319064-A1 POLYMER COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2016-11-03 US disclosed
US-9453100-B2 Polymer compositions and methods NOVOMER, INC. (US) 2016-09-27 US disclosed
US-20160264728-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2016-09-15 US disclosed
US-9399701-B2 Polymer compositions and methods NOVOMER, INC. (US) 2016-07-26 US disclosed
US-4457806-A 2,6-DINITRO-4-ETHYLPHENOL THE SHERWIN-WILLIAMS COMPANY (US) 1984-07-03 US disclosed
US-4442048-A Method and apparatus for controlling the formation of polymer accumulations during distillation of a vinylaromatic monomer COSDEN TECHNOLOGY, INC. (US) 1984-04-10 US disclosed
US-4442115-A ANTI-ASTHMA MAY & BAKER LIMITED (GB) 1984-04-10 US disclosed
US-4396462-A Method for inhibiting the formation of polymerized vinylaromatic compounds during distillative purification of vinylaromatic monomer COSDEN TECHNOLOGY, INC. (US) 1983-08-02 US disclosed
US-4376678-A Method of inhibiting polymerization of vinyl aromatic compounds AMERICAN HOECHST CORPORATION (US) 1983-03-15 US disclosed
US-4374000-A Method for controlling the formation of polymer accumulations during distillation of a vinylaromatic monomer COSDEN TECHNOLOGY, INC. (US) 1983-02-15 US disclosed
EP-0062625-A1 Process for the production of vinyltoluene COSDEN TECHNOLOGY INC. (US) 1982-10-13 EP disclosed
US-4132601-A DISTILLATION IN PRESENCE OF 3-NITRO-2,5-CRESOTIC ACID OR 3-NITRO-2,5-CRESOTALDEHYDE COSDEN TECHNOLOGY, INC. (US) 1979-01-02 US disclosed
US-4132601-A DISTILLATION IN PRESENCE OF 3-NITRO-2,5-CRESOTIC ACID OR 3-NITRO-2,5-CRESOTALDEHYDE COSDEN TECHNOLOGY, INC. (US) 1979-01-02 US disclosed