SCHEMBL8977978

SCHEMBL8977978

CCCCCCCCCCCCCCCCCCOCC(COC(C)=O)NC(C)=O

nearest known ligand 0.73

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 9/20 0.73
PLA2G2A P14555 4/20 0.50
CES2 O00748 1/20 0.45
TLR2 O60603 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9863891 0.84 PLA2G2C (0.77) PLA2G2CPLA2G2ACES2TLR2
SCHEMBL8978120 0.83 PLA2G2C (0.65) PLA2G2CPLA2G2A
SCHEMBL9959246 0.83 PLA2G2C (0.65) PLA2G2CPLA2G2A
SCHEMBL27273573 0.80 TDP1 (0.42) PLA2G2CPLA2G2A
SCHEMBL9863482 0.80 PLA2G2C (0.57) PLA2G2CTLR2
SCHEMBL9863442 0.79 PLA2G2C (0.56) PLA2G2CPLA2G2ATLR2
Iodide SCHEMBL9863538 0.79 PLA2G2C (0.56) PLA2G2C
SCHEMBL10894031 0.78 USP2 (0.61) PLA2G2CCES2
SCHEMBL27966543 0.78 USP2 (0.61) PLA2G2CCES2
SCHEMBL27966325 0.78 USP2 (0.61) PLA2G2CCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5482965-A PROMOTERS FOR TRANSDERMAL ADMINISTRATION OF DRUGS RAJADHYAKSHA VITHAL J (US) 1996-01-09 US claimed
EP-0576605-A4 COMPOSITIONS AND METHOD COMPRISING AMINOALCOHOL DERIVATIVES AS MEMBRANE PENETRATION ENHANCERS RAJADHYAKSHA VITHAL J (US) 1994-06-08 EP claimed
EP-0576605-A1 COMPOSITIONS AND METHOD COMPRISING AMINOALCOHOL DERIVATIVES AS MEMBRANE PENETRATION ENHANCERS THERAPEUTIC PATCH RESEARCH N.V. (US) 1994-01-05 EP claimed
WO-1992016236-A1 COMPOSITIONS AND METHOD COMPRISING AMINOALCOHOL DERIVATIVES AS MEMBRANE PENETRATION ENHANCERS RAJADHYAKSHA VITHAL J (US) 1992-10-01 WO claimed
US-5482965-A PROMOTERS FOR TRANSDERMAL ADMINISTRATION OF DRUGS RAJADHYAKSHA VITHAL J (US) 1996-01-09 US disclosed
EP-0576605-A4 COMPOSITIONS AND METHOD COMPRISING AMINOALCOHOL DERIVATIVES AS MEMBRANE PENETRATION ENHANCERS RAJADHYAKSHA VITHAL J (US) 1994-06-08 EP disclosed
EP-0576605-A1 COMPOSITIONS AND METHOD COMPRISING AMINOALCOHOL DERIVATIVES AS MEMBRANE PENETRATION ENHANCERS THERAPEUTIC PATCH RESEARCH N.V. (US) 1994-01-05 EP disclosed
WO-1992016236-A1 COMPOSITIONS AND METHOD COMPRISING AMINOALCOHOL DERIVATIVES AS MEMBRANE PENETRATION ENHANCERS RAJADHYAKSHA VITHAL J (US) 1992-10-01 WO disclosed