Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 9/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17309228 | 0.86 | PLA2G2C (0.57) | PLA2G2CUSP2PLA2G2ACES2HTT | |
| SCHEMBL8977978 | 0.84 | PLA2G2C (0.73) | PLA2G2CPLA2G2ACES2TLR2 | |
| SCHEMBL19079076 | 0.84 | PLA2G2C (0.58) | PLA2G2CUSP2 | |
| SCHEMBL16350166 | 0.81 | PLA2G2C (0.58) | PLA2G2C | |
| SCHEMBL24339846 | 0.80 | USP2 (0.59) | PLA2G2CUSP2HTT | |
| SCHEMBL24339807 | 0.80 | USP2 (0.59) | PLA2G2CUSP2HTT | |
| SCHEMBL10701026 | 0.78 | USP2 (0.58) | PLA2G2CUSP2HTT | |
| SCHEMBL24340432 | 0.78 | PRSS1 (0.49) | PLA2G2C | |
| SCHEMBL24340434 | 0.78 | PRSS1 (0.49) | PLA2G2C | |
| SCHEMBL17817572 | 0.78 | PLA2G2C (0.58) | PLA2G2CPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025005-A | Preventive or therapeutic agents for circulatory diseases, allergic disorders; antineoplastic agent; inhibitor for platelet activating factor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-18 | — | — | US | disclosed |
| US-4737518-A | ANTIALLERGENS, ANTINEOPLASTICS, ANTICOAGULANTS, CIRCULATORY DISEASES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-04-12 | — | — | US | disclosed |
| US-4640913-A | Phosphocholine derivatives having antihypertensive action | AMERICAN CYANAMID COMPANY (US) | 1987-02-03 | — | — | US | disclosed |
| EP-0157609-A2 | Lipid derivatives their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-10-09 | — | — | EP | disclosed |