Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.61 |
| ▸ | PDE5A | O76074 | 6/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MIF | P14174 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816050 | 1.00 | PDE4B (0.61) | PDE4BPDE5APDE3AALDH1A1MIF | |
| SCHEMBL3197152 | 0.89 | PDE4B (0.76) | PDE4BPDE5APDE3AALDH1A1MIF | |
| SCHEMBL3203334 | 0.78 | PDE4B (0.81) | PDE4BPDE5APDE3AALDH1A1MIF | |
| SCHEMBL5848990 | 0.78 | ALDH1A1 (0.51) | PDE4BPDE5APDE3AALDH1A1MIF | |
| SCHEMBL7815839 | 0.78 | ALDH1A1 (0.51) | PDE4BPDE5APDE3AALDH1A1MIF | |
| SCHEMBL653503 | 0.77 | PDE4B (0.76) | PDE4BPDE5APDE3AALDH1A1MIF | |
| SCHEMBL655570 | 0.77 | MIF (0.78) | PDE4BPDE5APDE3AALDH1A1MIF | |
| SCHEMBL11721382 | 0.77 | MIF (0.54) | PDE4BPDE5APDE3AALDH1A1MIF | |
| Hydrochloric Acid SCHEMBL9137257 | 0.76 | PDE4B (0.50) | PDE4BPDE5APDE3AALDH1A1MIF | |
| Hydrochloric Acid SCHEMBL8977958 | 0.76 | PDE4B (0.50) | PDE4BPDE5APDE3AALDH1A1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525480-A | USED FOR DETERMINATION OF HYDROLASES; COLORIMETRIC ANALYSIS | BOEHRINGER MANNHEIM GMBH (DE) | 1996-06-11 | — | — | US | disclosed |
| US-5457200-A | Oxidative coupling reactions for determination of hydrogen peroxide | BOEHRINGER MANNHEIM (DE) | 1995-10-10 | — | — | US | disclosed |
| US-5334505-A | For colorimetric determination of hydrolases | BOEHRINGER MANNHEIM GMBH (DE) | 1994-08-02 | — | — | US | disclosed |
| US-5234818-A | Detecting hydrogen peroxide, peroxidase by oxidative coupling with electron-rich aromatic compound | BOEHRINGER MANNHEIM GMBH (DE) | 1993-08-10 | — | — | US | disclosed |