SCHEMBL8978029

SCHEMBL8978029

[SiH2]=[Zr](C1=CC=CC1)(c1ccccc1)(c1ccccc1)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
PNMT P11086 1/20 0.35
SRD5A2 P31213 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1685241 0.99 NPC1 (0.36) NPC1RAB9APNMTSRD5A2
Hydrochloric Acid SCHEMBL5081177 0.92 NPC1 (0.34) NPC1RAB9APNMT
SCHEMBL9943457 0.90 NPC1 (0.33) NPC1RAB9APNMT
Hydrochloric Acid SCHEMBL5080626 0.89 NPC1 (0.33) NPC1RAB9APNMT
Hydrochloric Acid SCHEMBL2869481 0.84 NPC1 (0.36) NPC1RAB9APNMTSRD5A2
SCHEMBL8855722 0.83 NPC1 (0.39) NPC1RAB9APNMTSRD5A2
Hydrochloric Acid SCHEMBL4976446 0.82 NPC1 (0.36) NPC1RAB9APNMTSRD5A2
Hydrochloric Acid SCHEMBL7256944 0.82
Hydrochloric Acid SCHEMBL3126691 0.82 PNMT (0.42) NPC1RAB9APNMTSRD5A2
Hydrochloric Acid SCHEMBL814187 0.82 NPC1 (0.38) NPC1RAB9APNMTSRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0709405-A1 Process for the production of olefin polymers Tosoh Corporation (JP) 1996-05-01 EP disclosed