Acrylamide

Acrylamide

SCHEMBL8978032

C=CC(N)=O.C=CC(N)=O.C=NC(N)=O

nearest known ligand 0.69

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Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.69
TSHR P16473 1/20 0.69
FGFR4 P22455 1/20 0.69
CYP3A4 P08684 1/20 0.37
HPGD P15428 1/20 0.37
EHMT2 Q96KQ7 1/20 0.37
HSD17B10 Q99714 1/20 0.37
EHMT1 Q9H9B1 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylamide SCHEMBL10523241 1.00 ALDH1A1 (0.69) ALDH1A1TSHRFGFR4CYP3A4HPGD
Acrylamide SCHEMBL28055247 0.84
SCHEMBL28249860 0.83 ALDH1A1 (0.50) ALDH1A1TSHRFGFR4CYP3A4HPGD
Acrylamide SCHEMBL170034 0.83 TSHR (1.00) ALDH1A1TSHRFGFR4CYP3A4HPGD
SCHEMBL101239 0.83
Acrylamide SCHEMBL183292 0.83 TSHR (1.00) ALDH1A1TSHRFGFR4CYP3A4HPGD
Acrylamide SCHEMBL1332254 0.83
Acrylamide SCHEMBL3051 0.83
Acrylamide SCHEMBL1332245 0.83
Acrylamide SCHEMBL27673722 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5567608-A N,N-DIALKYLACRYLAMIDE CONTAINING POLYMER NITTO CHEMICAL INDUSTRY CO., LTD. (JP) 1996-10-22 US disclosed
EP-0202976-B1 PROCESS FOR THE PREPARATION OF UREA ACRYL DERIVATIVES NORSOLOR S.A. (FR) 1988-07-13 EP disclosed
EP-0202976-A1 Process for the preparation of urea acryl derivatives NORSOLOR S.A. (FR) 1986-11-26 EP disclosed