Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pyridine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 5/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL27726395 | 0.97 | TSHR (0.50) | TSHRNAPRTTDP1ALDH1A1LOXL2 | |
| Pyridine SCHEMBL4592912 | 0.84 | TSHR (0.64) | TSHRNAPRTTDP1ALDH1A1 | |
| Pyridine SCHEMBL27274943 | 0.84 | TSHR (0.64) | TSHRNAPRTTDP1LOXL2CHRNA7 | |
| Pyridine SCHEMBL2471872 | 0.84 | TSHR (0.64) | TSHRNAPRTTDP1ALDH1A1 | |
| Pyridine SCHEMBL2512471 | 0.84 | TSHR (0.64) | TSHRNAPRTTDP1LOXL2CHRNA7 | |
| Benzene SCHEMBL1227479 | 0.80 | TSHR (0.73) | TSHRTDP1ALDH1A1LOXL2CYP2A6 | |
| Pyridine SCHEMBL17026694 | 0.79 | TSHR (0.56) | TSHRNAPRTTDP1ALDH1A1 | |
| Pyridine SCHEMBL5833445 | 0.79 | TSHR (0.56) | TSHRNAPRTTDP1LOXL2CHRNA7 | |
| Pyridine SCHEMBL8328719 | 0.77 | — | — | |
| Benzene SCHEMBL27952644 | 0.77 | TSHR (0.67) | TSHRTDP1ALDH1A1LOXL2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-218692092-U | Washing device is used in production of pyridone ethanolamine salt | 嘉祥新海成化工科技有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-218544390-U | Heat preservation device for preparing pyridone ethanolamine salt | 嘉祥新海成化工科技有限公司 | 2023-02-28 | — | — | CN | claimed |
| CN-218435034-U | Organic solvent recovery unit of pyridine ethanolamine salt production | 嘉祥新海成化工科技有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-218076460-U | Preparation pyridone is crystallization kettle for ethanolamine salt | 菏泽新东方日化科技有限公司 | 2022-12-20 | — | — | CN | claimed |
| CN-115124461-A | Preparation process of antiseptic bacteriostatic pyridone ethanolamine salt | 菏泽新东方日化科技有限公司 | 2022-09-30 | — | — | CN | claimed |
| CN-216573008-U | Temperature control device for preparing pyridone ethanolamine salt | 烟台东方化学有限公司 | 2022-05-24 | — | — | CN | claimed |
| CN-216547786-U | Heat preservation device for preparing pyridone ethanolamine salt | 烟台东方化学有限公司 | 2022-05-17 | — | — | CN | claimed |
| CN-210933877-U | Crystallization device is used in production of pyridone ethanolamine salt | 嘉祥新海成化工科技有限公司 | 2020-07-07 | — | — | CN | claimed |
| CN-210905040-U | Dry crystallization device of pyridine ethanolamine salt | 嘉祥新海成化工科技有限公司 | 2020-07-03 | — | — | CN | claimed |
| CN-210905013-U | Pyridone ethanolamine salt distillation concentration kettle | 嘉祥新海成化工科技有限公司 | 2020-07-03 | — | — | CN | claimed |
| CN-210794387-U | Pyridine ethanolamine salt packaging and storing device | 嘉祥新海成化工科技有限公司 | 2020-06-19 | — | — | CN | claimed |
| CN-101961506-A | Composite nano biological bone glue with osteogenesis inducing activity and preparation method thereof | SECOND PEOPLES HOSPITAL SHENZHEN | 2011-02-02 | — | — | CN | claimed |
| JP-63008374-A | — | — | None | — | — | JP | disclosed |
| CN-218692092-U | Washing device is used in production of pyridone ethanolamine salt | 嘉祥新海成化工科技有限公司 | 2023-03-24 | — | — | CN | disclosed |
| CN-218544390-U | Heat preservation device for preparing pyridone ethanolamine salt | 嘉祥新海成化工科技有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-218544390-U | Heat preservation device for preparing pyridone ethanolamine salt | 嘉祥新海成化工科技有限公司 | 2023-02-28 | — | — | CN | disclosed |
| EP-0708686-A1 | FUNCTIONAL GROUP CONTAINING ACTIVATED CARBONS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN (GB) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995001838-A1 | FUNCTIONAL GROUP CONTAINING ACTIVATED CARBONS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1995-01-19 | — | — | WO | disclosed |
| JP-S638374-A | PYRIDINE ETHANOL AMINE DERIVATIVE | HOFFMANN LA ROCHE | 1988-01-14 | — | — | JP | disclosed |
| US-4439433-A | CEPHALOSPORIN ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1984-03-27 | — | — | US | disclosed |