Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 16/20 | 0.40 |
| ▸ | CTSD | P07339 | 4/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978115 | 1.00 | BACE1 (0.40) | BACE1CTSDPTGS1GSTK1MME | |
| SCHEMBL30862102 | 0.93 | BACE1 (0.38) | BACE1CTSDMMEFOLH1 | |
| SCHEMBL30008175 | 0.93 | BACE1 (0.40) | BACE1CTSDMME | |
| SCHEMBL29378004 | 0.89 | MME (0.37) | BACE1MME | |
| SCHEMBL30782660 | 0.89 | BACE1 (0.39) | BACE1CTSDMME | |
| SCHEMBL30442348 | 0.89 | BACE1 (0.49) | BACE1CTSD | |
| SCHEMBL31453841 | 0.88 | DPP4 (0.39) | BACE1CTSD | |
| SCHEMBL30272504 | 0.87 | BACE1 (0.37) | BACE1CTSDMME | |
| SCHEMBL29900923 | 0.87 | MME (0.37) | MME | |
| SCHEMBL29842532 | 0.87 | NAALAD2 (0.38) | BACE1MMEFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516657-A | Baculovirus vectors for expression of secretory and membrane-bound proteins | CAMBRIDGE BIOTECH CORPORATION (US) | 1996-05-14 | — | — | US | disclosed |