Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 11/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 5/20 | 0.34 |
| ▸ | FNTB | P49356 | 5/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29378004 | 0.93 | MME (0.37) | BACE1MMEFNTAFNTBPGGT1B | |
| SCHEMBL30862102 | 0.93 | BACE1 (0.38) | BACE1CTSDBMP1MME | |
| SCHEMBL8978115 | 0.93 | BACE1 (0.40) | BACE1CTSDMME | |
| SCHEMBL8978124 | 0.93 | BACE1 (0.40) | BACE1CTSDMME | |
| SCHEMBL29476635 | 0.92 | BMP1 (0.38) | BACE1BMP1FNTAFNTBPGGT1B | |
| SCHEMBL30211127 | 0.92 | FOLH1 (0.40) | BMP1FNTAFNTBPGGT1B | |
| SCHEMBL29833168 | 0.88 | BACE1 (0.45) | BACE1CTSDBMP1 | |
| SCHEMBL29395252 | 0.88 | MME (0.46) | MMEFNTAFNTBPGGT1B | |
| SCHEMBL31573788 | 0.87 | FOLH1 (0.36) | BACE1BMP1MMEFNTAFNTB | |
| SCHEMBL30477910 | 0.86 | MME (0.41) | MMEFNTAFNTBPGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109152822-B | Broth microdilution method for assessing and determining minimum inhibitory concentration of antimicrobial polypeptide | 抗非特公司 | 2023-12-05 | — | — | CN | disclosed |
| US-20230277617-A1 | BIOFILM PREVENTION, DISRUPTION AND TREATMENT WITH BACTERIOPHAGE LYSIN | CONTRAFECT CORPORATION | 2023-09-07 | — | — | US | disclosed |
| CN-116603056-A | Enhancement of blood components with antibacterial activity of lysate proteins, method and use thereof | 康特拉费克特公司 | 2023-08-18 | — | — | CN | disclosed |
| US-11524046-B2 | Biofilm prevention, disruption and treatment with bacteriophage lysin | CONTRAFECT CORPORATION (US) | 2022-12-13 | — | — | US | disclosed |