Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29239 | 0.86 | TSHR (0.50) | ALDH1A1MAPTTSHRGAATP53 | |
| SCHEMBL29435133 | 0.86 | TSHR (0.50) | ALDH1A1MAPTTSHRGAATP53 | |
| Water SCHEMBL27875928 | 0.84 | TSHR (0.47) | ALDH1A1MAPTTSHRGAATP53 | |
| Lithium Ion SCHEMBL19732623 | 0.84 | TSHR (0.47) | ALDH1A1MAPTTSHRGAATP53 | |
| Fluoride SCHEMBL27770917 | 0.84 | TSHR (0.47) | ALDH1A1MAPTTSHRGAATP53 | |
| Hydrochloric Acid SCHEMBL6421167 | 0.84 | TSHR (0.47) | ALDH1A1MAPTTSHRGAATP53 | |
| Bromide SCHEMBL11815049 | 0.84 | TSHR (0.47) | ALDH1A1MAPTTSHRGAATP53 | |
| Hydrochloric Acid SCHEMBL2869837 | 0.84 | TSHR (0.47) | ALDH1A1MAPTTSHRGAATP53 | |
| SCHEMBL21065735 | 0.84 | TSHR (0.47) | ALDH1A1MAPTTSHRGAATP53 | |
| Bromide SCHEMBL27593416 | 0.84 | TSHR (0.47) | ALDH1A1MAPTTSHRGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378930-B1 | Cyclic urea derivative | NIPPON PAINT CO LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0378930-A1 | Cyclic urea derivative | NIPPON PAINT CO., LTD. (JP) | 1990-07-25 | — | — | EP | disclosed |