SCHEMBL8978186

SCHEMBL8978186

C=CCC([C]=O)CCCCCC/C=C\C/C=C\CCCCC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
F7 P08709 4/20 0.46
F3 P13726 4/20 0.46
KDM4E B2RXH2 3/20 0.46
PPARG P37231 3/20 0.46
PPARD Q03181 3/20 0.46
PPARA Q07869 3/20 0.46
FABP3 P05413 3/20 0.46
FFAR1 O14842 3/20 0.46
PTGS1 P23219 2/20 0.46
DUSP3 P51452 1/20 0.46
PTPN7 P35236 1/20 0.46
LMNA P02545 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP19A1 P11511 1/20 0.46
FABP4 P15090 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
GNA15 P30679 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9467703 0.88 TRPV1 (0.52) ALDH1A1F7F3KDM4EPPARG
SCHEMBL9118049 0.88 TRPV1 (0.52) ALDH1A1F7F3KDM4EPPARG
SCHEMBL8364113 0.88 TRPV1 (0.52) ALDH1A1F7F3KDM4EPPARG
SCHEMBL7047578 0.87 TSHR (0.40) ALDH1A1PPARDFFAR1LMNATSHR
SCHEMBL11051344 0.87 TSHR (0.40) ALDH1A1PPARDFFAR1LMNATSHR
SCHEMBL9466160 0.86 TRPV1 (0.50) ALDH1A1F7F3KDM4EPPARG
SCHEMBL585816 0.86 TSHR (0.37) ALDH1A1FFAR1TSHRFFAR4
SCHEMBL9467695 0.84 TRPV1 (0.49) ALDH1A1F7F3KDM4EPPARG
SCHEMBL9467038 0.84 TRPV1 (0.49) ALDH1A1F7F3KDM4EPPARG
SCHEMBL3050132 0.84 FFAR1 (0.49) F7F3PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708645-A1 USE OF COMPOUNDS WHICH INHIBIT PHOSPHATIDIC ACID FORMATION FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF CANCER CELL THERAPEUTICS, INC. (US) 1996-05-01 EP disclosed
WO-1995024199-A2 USE OF COMPOUNDS WHICH INHIBIT PHOSPHATIDIC ACID FORMATION FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF CANCER CELL THERAPEUTICS, INC. (US) 1995-09-14 WO disclosed