SCHEMBL3050132

SCHEMBL3050132

CCCCCCCCCCCC=CCC([C]=O)CCCCCCCCCCCCCC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.49
FFAR4 Q5NUL3 1/20 0.49
FAAH O00519 5/20 0.47
TRPV1 Q8NER1 1/20 0.47
TERT O14746 3/20 0.42
PTPN1 P18031 3/20 0.42
PPARG P37231 3/20 0.42
PPARD Q03181 3/20 0.42
PPARA Q07869 3/20 0.42
CYP1A2 P05177 2/20 0.42
MAPT P10636 2/20 0.42
CYP2C19 P33261 2/20 0.42
BLM P54132 2/20 0.42
HSD17B10 Q99714 2/20 0.42
FABP4 P15090 2/20 0.42
KMT2A Q03164 2/20 0.42
GMNN O75496 1/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11507798 0.93 FAAH (0.47) FFAR1FFAR4FAAHTRPV1TERT
SCHEMBL10583681 0.91 FAAH (0.52) FFAR1FFAR4FAAHTRPV1TERT
SCHEMBL15015524 0.91 FAAH (0.52) FFAR1FFAR4FAAHTRPV1TERT
SCHEMBL9467075 0.91 FAAH (0.52) FFAR1FFAR4FAAHTRPV1TERT
SCHEMBL6465319 0.91 FAAH (0.52) FFAR1FFAR4FAAHTRPV1TERT
SCHEMBL9467020 0.91 FAAH (0.52) FFAR1FFAR4FAAHTRPV1TERT
SCHEMBL151797 0.91 FAAH (0.52) FFAR1FFAR4FAAHTRPV1TERT
SCHEMBL6672341 0.91 FAAH (0.52) FFAR1FFAR4FAAHTRPV1TERT
SCHEMBL9466962 0.89 FAAH (0.50) FFAR1FFAR4FAAHTRPV1TERT
SCHEMBL9467790 0.87 FAAH (0.48) FFAR1FFAR4FAAHTRPV1TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100172967-A1 COMPOUND MODIFIED WITH GLYCEROL DERIVATIVE KYOWA HAKKO KIRIN CO., LTD. (JP) 2010-07-08 US disclosed
US-7696359-B2 Compound modified with glycerol derivative KYOWA HAKKO KIRIN CO., LTD. (JP) 2010-04-13 US disclosed
US-20060280784-A1 Compound modified with glycerol derivative KYOWA HAKKO KOGYO CO., LTD. (JP) 2006-12-14 US disclosed
EP-1666486-A1 COMPOUND MODIFIED WITH GLYCEROL DERIVATIVE Kyowa Hakko Kogyo Co., Ltd (JP) 2006-06-07 EP disclosed
EP-0285178-B1 Mannobiose derivatives MEITO SANGYO KK (JP) 1997-02-12 EP disclosed
EP-0680974-A1 Novel muramyldipeptide derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1995-11-08 EP disclosed
US-5292506-A L-alanine derivative DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1994-03-08 US disclosed
EP-0348942-B1 LIPID MEMBRANE STRUCTURES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1992-12-09 EP disclosed
US-5141751-A Drug delivery for antitumor agent; mass-reproduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1992-08-25 US disclosed
EP-0487909-A2 Novel muramyldipeptide derivatives and influenza vaccine comprising the derivatives DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1992-06-03 EP disclosed
US-4983725-A Liposomes with affinity for liver cells MEITO SANGYO CO., LTD. (JP) 1991-01-08 US disclosed
EP-0348942-A2 Lipid membrane structures DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1990-01-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060280784-A1 Compound modified with glycerol derivative MRGPRX1, MRGPRX2, NPC1L1 FFAR1 632/4885FFAR4 704/4885FAAH 1915/4885
US-20100172967-A1 COMPOUND MODIFIED WITH GLYCEROL DERIVATIVE NPC1L1, SGMS1, SCARB1 FFAR1 543/4885FFAR4 650/4885FAAH 1858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.