Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3510782 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1LMNAHCAR2 | |
| SCHEMBL8978172 | 0.79 | PRSS1 (0.51) | ALDH1A1L3MBTL1LMNATDP1KMT2A | |
| SCHEMBL2587934 | 0.78 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1LMNAHCAR2 | |
| SCHEMBL1177836 | 0.77 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1LMNAHCAR2 | |
| SCHEMBL2465566 | 0.76 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1LMNAHCAR2 | |
| SCHEMBL7686423 | 0.76 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1LMNAHCAR2 | |
| SCHEMBL3803222 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1LMNAHCAR2 | |
| SCHEMBL14674775 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1LMNAHCAR2 | |
| SCHEMBL958928 | 0.76 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNAHCAR2 | |
| SCHEMBL13248936 | 0.76 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1LMNAHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0378930-B1 | Cyclic urea derivative | NIPPON PAINT CO LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5385985-A | Cyclic urea derivative | NIPPON PAINT CO., LTD. (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0378930-A1 | Cyclic urea derivative | NIPPON PAINT CO., LTD. (JP) | 1990-07-25 | — | — | EP | disclosed |