Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 7/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 4/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | PRKCG | P05129 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | LYN | P07948 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MARK3 | P27448 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388167 | 0.81 | CHRM3 (0.40) | ADORA1ADORA3ADORA2AADORA2BCTSL | |
| Hydrochloric Acid SCHEMBL7029936 | 0.80 | CHRM3 (0.39) | ADORA1ADORA3ADORA2AADORA2BCTSL | |
| SCHEMBL1387953 | 0.79 | CTSL (0.47) | ADORA1ADORA3ADORA2AADORA2BCTSL | |
| Hydrochloric Acid SCHEMBL7028301 | 0.79 | CTSL (0.46) | ADORA1ADORA3ADORA2AADORA2BCTSL | |
| SCHEMBL1388124 | 0.79 | CTSL (0.48) | ADORA1ADORA3ADORA2AADORA2BCTSL | |
| SCHEMBL8396714 | 0.78 | CTSL (0.37) | ADORA1ADORA3ADORA2AADORA2BCTSL | |
| Hydrochloric Acid SCHEMBL7023573 | 0.78 | CTSL (0.47) | ADORA1ADORA3ADORA2AADORA2BCTSL | |
| SCHEMBL1387905 | 0.70 | CHRM3 (0.48) | ADORA1ADORA3ADORA2AADORA2BCTSL | |
| Hydrochloric Acid SCHEMBL7027686 | 0.69 | CHRM3 (0.47) | ADORA1ADORA3ADORA2AADORA2BCTSL | |
| SCHEMBL8397096 | 0.69 | CTSL (0.41) | ADORA1ADORA3ADORA2AADORA2BCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705265-A1 | NOVEL CHEMICAL COMPOUNDS HAVING PDE-IV INHIBITION ACTIVITY | Euroceltique S.A. (LU) | 1996-04-10 | — | — | EP | claimed |