Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7028961 | 0.99 | YTHDC1 (0.39) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1387933 | 0.83 | YTHDC1 (0.41) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7027845 | 0.82 | YTHDC1 (0.40) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1388102 | 0.80 | YTHDC1 (0.41) | YTHDC1CYP11B2CCNB2CDK1CCNB1 | |
| SCHEMBL1388397 | 0.79 | PDE10A (0.43) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7742137 | 0.79 | YTHDC1 (0.40) | YTHDC1CYP11B2CCNB2CDK1CCNB1 | |
| SCHEMBL1388327 | 0.78 | MAPK13 (0.34) | YTHDC1CYP11B2CCNA2CDK2CCNA1 | |
| Hydrochloric Acid SCHEMBL7030283 | 0.78 | PDE10A (0.42) | YTHDC1PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL7028127 | 0.77 | MAPK13 (0.33) | YTHDC1CYP11B2CDK2MAPK13MAPK12 | |
| SCHEMBL1388108 | 0.70 | PDE10A (0.41) | PDE4APDE4BPDE4CPDE4DCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705265-A1 | NOVEL CHEMICAL COMPOUNDS HAVING PDE-IV INHIBITION ACTIVITY | Euroceltique S.A. (LU) | 1996-04-10 | — | — | EP | disclosed |