Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8371676 | 1.00 | HIF1A (0.55) | HIF1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8371678 | 1.00 | HIF1A (0.55) | HIF1AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8369852 | 0.93 | HIF1A (0.63) | HIF1AALDH1A1 | |
| SCHEMBL8399406 | 0.93 | HIF1A (0.63) | HIF1AALDH1A1 | |
| SCHEMBL8369854 | 0.93 | HIF1A (0.63) | HIF1AALDH1A1 | |
| SCHEMBL8369614 | 0.90 | HIF1A (0.64) | HIF1APTGER4POLBKMT2A | |
| SCHEMBL8369612 | 0.90 | HIF1A (0.64) | HIF1APTGER4POLBKMT2A | |
| SCHEMBL8369944 | 0.89 | HIF1A (0.56) | HIF1AALDH1A1POLBKMT2AFFAR1 | |
| SCHEMBL8096246 | 0.89 | HIF1A (0.56) | HIF1AALDH1A1POLBKMT2AFFAR1 | |
| SCHEMBL8096251 | 0.89 | HIF1A (0.56) | HIF1AALDH1A1POLBKMT2AFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535928-B1 | Process for producing intermediates for use in production of alkoxyiminoacetamides | SHIONOGI & CO (JP) | 1996-05-01 | — | — | EP | disclosed |
| US-5387714-A | Alpha-keto acid halide intermediate | SHIONOGI & CO., LTD. (JP) | 1995-02-07 | — | — | US | disclosed |
| EP-0535928-A2 | Process for producing intermediates for use in production of alkoxyiminoacetamides | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-04-07 | — | — | EP | disclosed |