Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | DDX3X | O00571 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5167952 | 0.84 | MAPT (0.55) | MAPTKMT2APOLBMEN1DDX3X | |
| SCHEMBL28826075 | 0.84 | ALDH1A1 (0.54) | MAPTKMT2APOLBMEN1DDX3X | |
| SCHEMBL8223354 | 0.84 | MEN1 (0.54) | MAPTKMT2APOLBMEN1DDX3X | |
| SCHEMBL29780605 | 0.84 | MEN1 (0.54) | MAPTKMT2APOLBMEN1DDX3X | |
| SCHEMBL27625427 | 0.81 | MAPT (0.58) | MAPTKMT2APOLBMEN1DDX3X | |
| SCHEMBL10714890 | 0.80 | MAPT (0.49) | MAPTKMT2APOLBMEN1HTT | |
| SCHEMBL16943226 | 0.76 | MAPT (0.56) | MAPTKMT2APOLBMEN1DDX3X | |
| SCHEMBL9122352 | 0.75 | KMT2A (0.59) | MAPTKMT2APOLBMEN1DDX3X | |
| SCHEMBL11775765 | 0.75 | SMN1; SMN2 (0.60) | MAPTKMT2APOLBMEN1DDX3X | |
| SCHEMBL9371484 | 0.75 | KMT2A (0.59) | MAPTKMT2APOLBMEN1DDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708757-A1 | BENZIMIDAZOLE-DERIVATIZED AZO COMPOUNDS AND POLYMERS DERIVED THEREFROM FOR NONLINEAR OPTICS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002581-A1 | BENZIMIDAZOLE-DERIVATIZED AZO COMPOUNDS AND POLYMERS DERIVED THEREFROM FOR NONLINEAR OPTICS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |
| US-5321084-A | Benzimidazole-derivatized azo compounds and polymers derived therefrom for nonlinear optics | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-06-14 | — | — | US | disclosed |