SCHEMBL8978480

SCHEMBL8978480

CC(C)=CCCC(C)=CCCC(C)CCCC(C)O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.52
ALDH1A1 P00352 2/20 0.50
ALOX15 P16050 2/20 0.50
KDM4E B2RXH2 1/20 0.49
SQLE Q14534 4/20 0.47
MAPT P10636 2/20 0.47
MEN1 O00255 1/20 0.47
CYP3A4 P08684 1/20 0.47
UGT1A1 P22309 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8978478 1.00 KMT2A (0.52) KMT2AALDH1A1ALOX15KDM4ESQLE
SCHEMBL7635315 0.89 ALOX15 (0.61) ALDH1A1ALOX15KDM4E
SCHEMBL8978499 0.89 ALOX15 (0.61) ALDH1A1ALOX15KDM4E
SCHEMBL8978519 0.88 ALOX15 (0.52) KMT2AALDH1A1ALOX15KDM4ESQLE
SCHEMBL8978516 0.88 ALOX15 (0.52) KMT2AALDH1A1ALOX15KDM4ESQLE
SCHEMBL2496377 0.86 KMT2A (0.64) KMT2AALDH1A1ALOX15KDM4ESQLE
SCHEMBL2495543 0.86 KMT2A (0.64) KMT2AALDH1A1ALOX15KDM4ESQLE
SCHEMBL8978471 0.86 KMT2A (0.64) KMT2AALDH1A1ALOX15KDM4ESQLE
SCHEMBL2495546 0.86 KMT2A (0.64) KMT2AALDH1A1ALOX15KDM4ESQLE
SCHEMBL871914 0.86 KMT2A (0.64) KMT2AALDH1A1ALOX15KDM4ESQLE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0577356-B1 Topical composition for preventing or treating acne vulgaris TAKASAGO PERFUMERY CO LTD (JP) 1996-05-01 EP disclosed
US-5344850-A Branched long chain alcohol, bactericide effective against Propionibacterium TAKASAGO INTERNATIONAL CORPORATION (JP) 1994-09-06 US disclosed
EP-0577356-A1 Topical composition for preventing or treating acne vulgaris Takasago International Corporation (JP) 1994-01-05 EP disclosed