Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | GFER | P55789 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978556 | 0.88 | ALDH1A1 (0.69) | TDP1ALDH1A1HPGDGFERKDM4E | |
| SCHEMBL8978582 | 0.80 | ALDH1A1 (0.71) | TDP1ALDH1A1HPGDKDM4EALOX15 | |
| SCHEMBL8978568 | 0.75 | KDM4E (0.63) | TDP1ALDH1A1HPGDGFERKDM4E | |
| SCHEMBL8978564 | 0.74 | TDP1 (0.69) | TDP1ALDH1A1HPGDGFERKDM4E | |
| SCHEMBL8931012 | 0.73 | ALDH1A1 (0.57) | TDP1ALDH1A1HPGDGFERKDM4E | |
| SCHEMBL8978522 | 0.73 | ALDH1A1 (0.73) | TDP1ALDH1A1HPGDGFERKDM4E | |
| SCHEMBL8978608 | 0.72 | ALDH1A1 (0.74) | TDP1ALDH1A1HPGDGFERKDM4E | |
| SCHEMBL8978565 | 0.72 | ALDH1A1 (0.63) | ALDH1A1HPGDGFERKDM4EHSD17B10 | |
| SCHEMBL8978575 | 0.71 | ALDH1A1 (1.00) | TDP1ALDH1A1HPGDGFERKDM4E | |
| SCHEMBL8978553 | 0.71 | ALDH1A1 (0.72) | TDP1ALDH1A1HPGDGFERKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489598-A | INHIBITS ADHESION OF MAC-1 TO ENDOTHELIAL CELLS, USEFUL FOR TREATING GASTRITIS INDUCED BY NONSTEROIDANTIINFLAMMATORY DRUGS IMFLAMMATORY BOWEL DISEASE OF ULCERATIVE COLITIS | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |