Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.69 |
| ▸ | HPGD | P15428 | 5/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.69 |
| ▸ | PPARG | P37231 | 2/20 | 0.69 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.69 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | GFER | P55789 | 2/20 | 0.69 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.69 |
| ▸ | PRNP | P04156 | 1/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | CHRNE | Q04844 | 1/20 | 0.56 |
| ▸ | RPA1 | P27694 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13983421 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDLMNARXFP1 | |
| SCHEMBL8978565 | 0.83 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDLMNARXFP1 | |
| SCHEMBL12768250 | 0.83 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDLMNARXFP1 | |
| SCHEMBL8978592 | 0.82 | KDM4E (1.00) | ALDH1A1KDM4EHPGDLMNARXFP1 | |
| SCHEMBL8978535 | 0.82 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDLMNARXFP1 | |
| SCHEMBL13983470 | 0.82 | ALDH1A1 (0.59) | ALDH1A1KDM4EHPGDLMNARXFP1 | |
| SCHEMBL7072642 | 0.80 | ALDH1A1 (0.81) | ALDH1A1KDM4EHPGDRXFP1PPARG | |
| SCHEMBL8978544 | 0.78 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDLMNARXFP1 | |
| SCHEMBL10189851 | 0.78 | TDP1 (0.73) | ALDH1A1KDM4EHPGDLMNARXFP1 | |
| SCHEMBL13983416 | 0.77 | ALDH1A1 (0.71) | ALDH1A1KDM4EHPGDLMNARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489598-A | INHIBITS ADHESION OF MAC-1 TO ENDOTHELIAL CELLS, USEFUL FOR TREATING GASTRITIS INDUCED BY NONSTEROIDANTIINFLAMMATORY DRUGS IMFLAMMATORY BOWEL DISEASE OF ULCERATIVE COLITIS | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |