Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | GFER | P55789 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978556 | 0.81 | ALDH1A1 (0.69) | ALDH1A1GFERKDM4ETDP1CYP1A2 | |
| SCHEMBL8978549 | 0.81 | ALDH1A1 (0.66) | ALDH1A1GFERKDM4ETDP1CYP1A2 | |
| SCHEMBL8978522 | 0.78 | ALDH1A1 (0.73) | ALDH1A1GFERKDM4ETDP1CYP1A2 | |
| SCHEMBL1543726 | 0.77 | TDP1 (0.57) | ALDH1A1GFERKDM4ETDP1CYP1A2 | |
| SCHEMBL8978574 | 0.77 | ALDH1A1 (0.68) | ALDH1A1GFERKDM4ETDP1CYP1A2 | |
| SCHEMBL8978537 | 0.77 | ALDH1A1 (0.56) | ALDH1A1GFERKDM4ETDP1CYP1A2 | |
| SCHEMBL8978575 | 0.75 | ALDH1A1 (1.00) | ALDH1A1GFERKDM4ETDP1CYP1A2 | |
| SCHEMBL8978553 | 0.75 | ALDH1A1 (0.72) | ALDH1A1GFERKDM4ETDP1CYP1A2 | |
| SCHEMBL8978540 | 0.75 | ALDH1A1 (0.59) | ALDH1A1GFERKDM4ETDP1CYP1A2 | |
| SCHEMBL8978608 | 0.74 | ALDH1A1 (0.74) | ALDH1A1GFERKDM4ETDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489598-A | INHIBITS ADHESION OF MAC-1 TO ENDOTHELIAL CELLS, USEFUL FOR TREATING GASTRITIS INDUCED BY NONSTEROIDANTIINFLAMMATORY DRUGS IMFLAMMATORY BOWEL DISEASE OF ULCERATIVE COLITIS | WARNER-LAMBERT COMPANY (US) | 1996-02-06 | — | — | US | disclosed |