Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.39 |
| ▸ | ACACB | O00763 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978955 | 0.92 | ACACB (0.42) | FFAR1ACACBFFAR4 | |
| SCHEMBL8978794 | 0.92 | HSD17B10 (0.52) | TSHRHSD17B10CYP2A6FFAR1CYP19A1 | |
| SCHEMBL9293685 | 0.91 | TRPV4 (0.42) | TSHRHSD17B10CYP2A6FFAR1ACACB | |
| SCHEMBL8979050 | 0.90 | HSD17B10 (0.58) | TSHRHSD17B10CYP2A6FFAR1CYP19A1 | |
| SCHEMBL8979032 | 0.89 | HSD17B10 (0.61) | TSHRHSD17B10CYP2A6FFAR1CYP19A1 | |
| SCHEMBL8978940 | 0.89 | HSD17B10 (0.61) | TSHRHSD17B10CYP2A6FFAR1CYP19A1 | |
| SCHEMBL8979113 | 0.89 | HSD17B10 (0.61) | TSHRHSD17B10CYP2A6FFAR1CYP19A1 | |
| SCHEMBL8978812 | 0.89 | HSD17B10 (0.61) | TSHRHSD17B10CYP2A6FFAR1CYP19A1 | |
| SCHEMBL8978828 | 0.89 | HSD17B10 (0.61) | TSHRHSD17B10CYP2A6FFAR1CYP19A1 | |
| SCHEMBL8978971 | 0.88 | ACACB (0.40) | CYP2A6FFAR1ACACBFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581272-B1 | Tolane derivatives, liquid crystal compositions containing the derivatives and liquid crystal display device using the compositions | SEIKO EPSON CORP (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5356558-A | Compatibility, high speed response | SEIKO EPSON CORPORATION (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0581272-A1 | Tolane derivatives, liquid crystal compositions containing the derivatives and liquid crystal display device using the compositions | SEIKO EPSON CORPORATION (JP) | 1994-02-02 | — | — | EP | disclosed |