Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978989 | 1.00 | ALDH1A1 (0.53) | ALDH1A1CYP2A6FFAR1FFAR4HAO1 | |
| SCHEMBL8979134 | 0.91 | GRM5 (0.42) | ALDH1A1CYP2A6FFAR1FFAR4CYP11B1 | |
| SCHEMBL8979037 | 0.90 | ALDH1A1 (0.57) | ALDH1A1CYP2A6FFAR1FFAR4HAO1 | |
| SCHEMBL9293782 | 0.90 | CYP11B1 (0.50) | ALDH1A1CYP2A6FFAR1FFAR4CYP11B1 | |
| SCHEMBL23335104 | 0.86 | CYP11B1 (0.45) | ALDH1A1CYP2A6FFAR1FFAR4CYP11B1 | |
| SCHEMBL7851710 | 0.85 | FFAR1 (0.39) | FFAR1FFAR4GRM5CA12CA2 | |
| SCHEMBL10091204 | 0.85 | FFAR1 (0.49) | ALDH1A1FFAR1FFAR4HAO1GRM5 | |
| SCHEMBL7858970 | 0.85 | FFAR1 (0.39) | FFAR1FFAR4GRM5CA12CA2 | |
| SCHEMBL10018724 | 0.84 | GRM5 (0.42) | ALDH1A1CYP2A6FFAR1FFAR4CYP11B1 | |
| SCHEMBL7858588 | 0.84 | GRM5 (0.42) | ALDH1A1CYP2A6FFAR1FFAR4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581272-B1 | Tolane derivatives, liquid crystal compositions containing the derivatives and liquid crystal display device using the compositions | SEIKO EPSON CORP (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5356558-A | Compatibility, high speed response | SEIKO EPSON CORPORATION (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0581272-A1 | Tolane derivatives, liquid crystal compositions containing the derivatives and liquid crystal display device using the compositions | SEIKO EPSON CORPORATION (JP) | 1994-02-02 | — | — | EP | disclosed |