Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 8/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.52 |
| ▸ | OXER1 | Q8TDS5 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | RXRA | P19793 | 2/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | F7 | P08709 | 7/20 | 0.52 |
| ▸ | F3 | P13726 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9407470 | 1.00 | ALDH1A1 (0.55) | ALDH1A1ALOX15CYP2D6PPARGCYP19A1 | |
| SCHEMBL9407472 | 1.00 | ALDH1A1 (0.55) | ALDH1A1ALOX15CYP2D6PPARGCYP19A1 | |
| SCHEMBL9407474 | 1.00 | ALDH1A1 (0.55) | ALDH1A1ALOX15CYP2D6PPARGCYP19A1 | |
| SCHEMBL3683935 | 1.00 | ALDH1A1 (0.55) | ALDH1A1ALOX15CYP2D6PPARGCYP19A1 | |
| SCHEMBL1564477 | 0.93 | — | — | |
| SCHEMBL841087 | 0.93 | — | — | |
| SCHEMBL841088 | 0.93 | — | — | |
| SCHEMBL31501796 | 0.90 | PPARA (0.50) | ALDH1A1ALOX15CYP2D6PPARGCYP19A1 | |
| SCHEMBL6899945 | 0.88 | PPARA (0.49) | ALDH1A1ALOX15PPARGCYP19A1FFAR1 | |
| SCHEMBL19830162 | 0.88 | PPARA (0.49) | ALDH1A1ALOX15CYP2D6PPARGCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334408-B2 | Analogs of alpha galactosylceramide and uses thereof | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 2012-12-18 | — | — | US | disclosed |
| US-20120269857-A1 | ANALOGS OF ALPHA GALACTOSYLCERAMIDE AND USES THEREOF | LUDWIG INSTITUTE FOR CANCER RESEARCH | 2012-10-25 | — | — | US | disclosed |
| US-8188313-B2 | Analogs of alpha galactosylceramide and uses thereof | THE UNIVERSITY OF BIRMINGHAM (GB) | 2012-05-29 | — | — | US | disclosed |
| US-20120034269-A1 | ANALOGS OF ALPHA GALACTOSYLCERAMIDE AND USES THEREOF | CERUNDOLO VINCENZO (GB) | 2012-02-09 | — | — | US | disclosed |
| US-8039670-B2 | Analogs of alpha galactosyceramide and uses thereof | LUDWIG INSTITUTE FOR CANCER RESEARCH (US) | 2011-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120034269-A1 | ANALOGS OF ALPHA GALACTOSYLCERAMIDE AND USES THEREOF | UGCG, CD69, GALC | ALDH1A1 2446/4885ALOX15 793/4885CYP2D6 3802/4885 |
| US-20120269857-A1 | ANALOGS OF ALPHA GALACTOSYLCERAMIDE AND USES THEREOF | UGCG, GALC, CD69 | ALDH1A1 2622/4885ALOX15 878/4885CYP2D6 3809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.